The Laboratory for Cellular & Molecular Engineering serves as a core facility and collaboration space for CSELS investigators and their research teams. Its goal is to provide resources and intellectual stimuli to facilitate cell-centric research spanning multiple length scales, from molecules to tissues.

The Laboratory for Cellular & Molecular Engineering provides communal wet-lab space, instrumentation, and scientific consultation in order to achieve this goal. Additions to the lab will be made in the near future to meet the growing needs of Center for Science and Engineering of Living Systems members. Access to computational resources belonging to specific CSELS-affiliated labs is also available to CSELS members.

Experimental Resources

Instrumentation

  • AKTA pure FPLC
  • Biosafety cabinets and incubators for cell culture
  • Jasco spectropolarimeter (CD)
  • Molecular Devices SpectraMax i3x multi-mode plate reader
  • Nikon Eclipse TE2000 microscope
  • PTI QuantaMaster fluorometer
  • Shimadzu HPLC
  • TECAN F200 plate readers (x2)

Experimental consultation

The Laboratory for Cellular & Molecular Engineering is led by Ammon E. Posey, PhD., CSELS assistant director. Posey serves as a scientific consultant for project development and experimental design, including custom instrumentation design and prototyping. He also provides instrument and methods training, and coordinates shared instrument usage.

Computational Resources

Computational infrastructure

State-of-the-art and growing computational resources belonging to specific CSELS-affiliated labs are available to CSELS members. Additional investments in shared computational resources are forthcoming.

Of note, Greg Bowman, assistant professor of biochemistry and molecular biophysics at Washington University School of Medicine in St. Louis, and CSELS-affiliated professor, is currently the director of Folding@Home, a resource to which CSELS members may obtain privileged access via Bowman.

Computational consultation

CSELS not only brings together investigators from engineering and basic sciences but also investigators with a variety of computational expertise. The collective computational expertise of CSELS-affiliated investigators is at the disposal of CSELS members.